CAS Registry Number
The isoflavone(Isoflavones) is one category the natural plant compound of the estrogen, and then be called a phytoestrogen, all have this composition in many plants,such as soybean, red flower clover, Zao coco, pomegranate, .Is red, suffer from insomnia to the high and dangerous flock, the menopause upsurge of the bone soft disease, the Zao move, melancholy, have no condition of illnesses, such as power, joint, muscle ache and heart palpitates...etc., the isoflavone alleviated result goodly.The research even finds live composition of using the isoflavone often, breast cancer and shoot a comparison of protecting the gland cancer to reduce
The introduction of the soybean isoflavone
The isoflavone is the most in the content in the soybean because of existing, so widespread call it is the soybean isoflavone(isoflavone).The soybean scientific term Glycine max, the Die form flower section, belongs to a year to get herbs.The seed near to spheroid, growing the skin milk yellow or black, the milk yellow calls yellow soybean, black call the black bean or black bean.
The soybean isoflavone is as early as or so was found namely to have weak estrogen result 50 years ago, is one of the main current of the natural plant hormone.For is been slighter and dared not women who take the hormone medicine the bitterness but the condition by the menopause condition of illness, provided another health care choice.
The soybean isoflavone content accounts for 0.2% of 100 cents of soybean to go to 0.4% about, particularly the Pei stalk in the content is the most high, can reach to 2.4%.Although have 12 kinds of isoflavones with different above structure in the soybean, currently with the content is the most and the most important of of gold Qiao the research of the plain flavonoid Genistein is most for very clear.The soybean isoflavone its function similar and female estrogen, so be called a phytoestrogen again, in order to understanding simply and easily, the city sells a merchandise to be called with"phytoestrogen" much.
Usually the soybean of one kilogram only can extract 17.5 soybean isoflavone of the milligrams, if want to reach a demand, needing to eat a great deal of soybean can reach result.For ising far-gone because of the flatulence, gout, glycouria can't in great quantities the one who take the bean ware, takes the effect that the soybean isoflavone extracts to then come to an a health care directly.
Exist soybean in of the type flavonoid vegetable has a lot of categories:
However the detection mainly has the soybean isoflavone of the physiology meaning as the Genistein, Daidzein and Glystein from many researches.
Genistein:The gold Qiao plain flavonoid, and then be called a dyestuff wood flavonoid
Daidzein:The wood quality plain flavonoid
Glycitein:Soybean plain flavonoid
The good soybean isoflavone also needs quantitative analysis of having science to pay genistein:Daidzein:The glycitein constitutes a comparison(the gold comparison 1.1:1.0:0.2), reserving in the soybean naturally constitute is not broken, can maintain the most basic biomedical science of soybean value.So the suggestion must check soybean to have the isoflavone composition genistein, daidzein and glycitein of the physiology value while choosing different Tong product of the usage soybean, its content would because species and extract a technique and have difference.
The special function of the soybean isoflavone:The phytoestrogen(phytoestrogen) soybean isoflavone the most widespread applied cognition lie in the related condition of illness that improves estrogen.The chemistry synthesized the hormone therapy HRT in early days be thought to will increase a coronary, stroke, the vein blood to bolt, breast cancer occurrence rate.The type of the usage natural soybean isoflavone estrogen function, similar can smooth physiology and menopause unwell, but the absolution cause cancer of threat, so become hormone gradually of in lieu of the main current of the therapy.
●"Double to function" of the phytoestrogen
Domestic and international scholar research point out, the soybean isoflavone can the function accept a body in the estrogen up, produce the physiology of the similar estrogen activity, but its function effect price is very low, about 1/100-1/1000, so also be called geniality of estrogen(the Weak estrogen), however have the effect of the anti- Estrogen(Antiestrogen).
It is most special to have "the Jie anti-" or"faintly and together the Gong differences body" of the estrogen two kinds of result in the meantime.
1.The Jie anti- competes a function:Secrete to the hormone normally, healthily young female, because the isoflavone structure and the pantheress hormone are close by, past can be subjected to the body competition to combine position and the pantheress hormone, obstruct to reduce the risk of breast cancer, cervical cancer because the excessive estrogen is combined by body with it.
2.Together Gong differences body:Secrete gradual decrease to the hormone, menopause women and speech, the soybean isoflavone can add the estrogen function, improving because the condition of illness that estrogen produce when descending.
Animality hormone:The physiology function mightiness, there is cancer-causing danger.
Plant hormone:The physiology function geniality, have no side effect.
If want to reduce the occurrence probability of the female cancer by adding the soybean isoflavone, should use, if wait for to the menopause to just start in the prevention of breast cancer, cervical cancer in the young beginning as early as possible is night 1:00, because this the female of the Hou is already gradual from the estrogen of the body natural decrease.The soybean isoflavone has to promote inside the born nature estrogen(the endogenous estrogens) toward 2-the metabolism path of the hydroxylated estrogens, and raise blood in 2-the specific value of the hydroxylestrone/16 alphas-hydroxylestrone, because of thinking a higher density in blood generally of 17-beta-estradiol, 4-with 16 alphas-hydroxylestrone and
● The absorption rate of the soybean isoflavone:Have no sugar Ji structure to absorb most easily
The soybean isoflavone has two kinds of types:The a kind of is the molecular weight is big, the activity goes together with the carbohydrate body isoflavone lowly, the bowel way the absorption rate only reaches to 20%.
Another a kind of is the molecular weight is smaller, the activity is high of to the carbohydrate body isoflavone, can reach 90% about at the absorption rate of the human body bowel way.
The natural soybean isoflavone has the sugar Ji mostly, is not easily absorbed by human body, need through the bowel inside the germ resolve a creation have no the sugar Ji of the soybean isoflavone just behaves the body absorption exploitation easily.
The isoflavone of the dissimilarity structure will have the different activity and the absorption rate:
Go together with the carbohydrate body isoflavone(the Glucoside Form):as Genistin, Daidzin, go together with the carbohydrate body molecular weight to compare greatly, the appetite way absorbs not easily, physiology can the utilization can only reach 20%.
Go to the carbohydrate body isoflavone(the Aglycone Form):As the Genistein, Daidzein, the molecular weight is smaller, can reach 90% about in the absorption rate of the human body bowel way.
Ferment sex bean to producted not, if the bean curd, bean is dry, all of soybean isoflavones that bean milk contains are lowly activities to go together with the carbohydrate body isoflavone, absorbing a rate not high.
Fermenting the bean ware includes flavor to increase, foods such as bean Shi, the Fu milk and sauce etc., these beans product in addition to having proper high-quality nourishment of soybean, also have abundant of to the carbohydrate body isoflavone, it is what in the soybean and bean curd original isoflavone through ferment conversion, but stronger than the original isoflavone function, and alter absorption.
If want with the soybean isoflavone vegetable extracted to be used as to maintain, have to also distinguish analyse the health care product in of isoflavone structure whether for ferment of to carbohydrate body isoflavone form.
Science of the soybean isoflavone studies
The physiology health care result of the soybean flavonoid vegetable can describe five major type about:
1.Prevent cardiovascular disease, reduce blood fat
As early as in 1999, the American food drugs FDA in the examination bureau declared formally, as long as contained more than 6.5 grams soybean egg whites and can mark related health care result of cardiovascular disease in each food.Because many anti-s of the science experiment certificate soybean flavonoid vegetables oxidize result, impersonation to cardiovascular have a role of protection.
It uses at with prevent the development of the artery hardening, its possible machine turns into:
1. The isoflavone genistein is the Lao An is sour to arouse enzyme to repress a thing, can by repressing the activity and Ning of the blood platelets to gather a function inhibits the formation that the blood bolts.Also maintain normally afferent reaction, as a result improved the development of the artery hardening.
2.The soybean isoflavone can reduce good cholesterol of not good cholesterol, increment, to blood vessel also is have the protection function.The soybean egg white can repress the cholesterol activity, the isoflavone content is more high, it reduces the effect of total cholesterol and the LDL cholesterol also more good, can
2.Delicate skin fair hairdressing result:
The function of the estrogen, in addition to maintenance the normally female physiology function also participates the metabolism that the skin organizes and fat outside.
The female secretes in 20-30 years old estrogen the most prosperous, at this time of the female has instinct of feeding the Yun life not only, there is also smooth and delicate rich elastic skin, exquisite and graceful full of curve of body Zi.
The medical science research proves a female from 30 years old hereafter, the ovary function started declining, the estrogen secreted gradual decrease, keeping to stop menstruating after, the estrogen level declines to valley bottom.So 30 years old later of female, back to go sex variety with the decrease and occurrence of the estrogen, as skin flexible decrease, the sheen disappears, appearing the crease and dye spot.
The skin distributes a great deal of estrogen to accept a body, and becomes the function of the estrogen importance organization organ, the soybean isoflavone is seen a natural phytoestrogen, can also be combined by body with the estrogen in the skin, reaching hairdressing and moistenning a function of protecting the skin, for improvement because the female endocrine causes of black spot, dark Chuang, aging dark sink to all have a help.
In addition the soybean isoflavone can also pass the free radicals of the surplus inside its nti- oxygenation clearance body, strengthening the ability that the skin resists ultraviolet ray thus, the prevention melanin, old-age spot and the formation of the liver spot, reach the result of the fair skin.The research report way of the United Stateses says the soybean isoflavone can absorb in the long wave ultraviolet ray, repressing the Lao ammonia in the body sour.
3.Slow female menopause condition of illness
The general women stop menstruating average age is 50 years old or so, but before stopping menstruating several annual conventions because the ovary function descends, causing the hormone cause shortage, and enter menopause.The female has after entering menopause of the person will have the red obvious upsurge, heart palpitates, skin dry Se, choler etc. condition of illness.
The estrogen secretes to reduce the influence that would cause to have:
1 influence a brain to the control of the body temperature, easy creation the upsurge is red, night sweat;If this kind of phenomenon appears in nighttime, will influence the sleep quality, causing to suffer from insomnia, weariness, sometimes will also accompany with headache.
2 cause the urethra epidermis organization become thin, the resistibility dies down, causing the nearby organization of urine bladder become in the meantime weak, may cause the urine incontinence.
3 bone substances run off, causing the bone soft disease, the women's cardiovascular disease increases after stopping menstruating, also lacking of with estrogen relevant.
Science experiment shows that taking 60 soybean egg white(contain a soybean flavonoid plain 135 milligramses about) consecution of the grams everyday is on all sides and can make the hot and dry feeling descend 33%, then can decline to 45% continuously for 12 weeks.At the physiology effect aspect, it has no the side effect of estrogen, but owns a similar to the estrogen physiology function, helping body to keep calcium quality and reducing menopause women to contract the probability of the cardiovascular disease, diabetes, for menopause because the hot and dry feeling that the unbalance produces of the hormone also has improvement function.
How does the soybean isoflavone improve menopause condition of illness?
The hormone of the menopause changes seem to sit mine ride, be a female
4.The prevention of the bone soft disease
Estrogen's the calcium quality absorption in the human body plays very important role.With the age increment, the bone density reduces gradually to also cause the bone fracture and bone soft easily, preventing better than treatment, in addition to the complement calcium quality, moderation of the complement soybean isoflavone prevent the calcium quality from running off is also rather important.
American orthopedics medical science would of the report point out, the natural isoflavone has already been confirmed having bone substance of promote synthesizes and represses the function that the bone substance runs off, the women give everyday after the experiment win for 47-57-year-old stop menstruating the soybean isoflavone with 54 mgs, the result confimation for stop menstruating the women have bone substance of reduce to run off and increases the function that the bone substance synthesizes and reaches result of increasing the bone substance density(BMD), but doesn't synthesize the side effect of the hormone after the bone soft.
The bone soft has been in the middle age ethnicity an important healthy problem, particularly is stop menstruating women, lack of to cause the bone substance run off quickly due to the estrogen, so the top of the medical science often cures with the hormone complement therapy(HRT), but through American long-term of tracking and finding the HRT has cause far-gone side effect of breast cancer and heart, so the plant hormone therapy, become a kind of can consider current effect again the therapy of the security.
5.The anti-cancer function machine turns
For and sex hormone the related cancer change, the soybean isoflavone also all has a function of repress.Have about 100 divide into 65 of animal the on trial manifestation soybean isoflavone has outstanding anti-cancer result(as the prevention of the cardiovascular disease, breast cancer, cervical cancer and prostate gland cancer), can repress the blood vessel of the cancer cell to increase to get a function, being to have falsely often the cell get
Usage and dosage
The soybean isoflavone is a kind of natural plant estrogen, wasing hading by a great deal of research support the rather obvious biomedical science is worth, almost having no the report of obvious side effect currently.However the soybean of one kilogram only can extract 17.5 soybean isoflavone of the milligrams, having to eat a great deal of soybean can reach result.Although a lot of expert's scholars promote the advantage that the edible soybean products, however some gout sufferers, diabetics, or to bean easily allergic flatulence, if want product to win to take from this tall Pu wood, high sugar soybean need of composition, opposite will also increase to body of burden.There are a lot of soybeans to producted all ising through the gene reformation, gene reformation food to threat of the human body health also is need to be considered, so still with extract of the soybean flavonoid vegetable will be better to being used as the nourishment complement.
Suggest everybody to make reference to take to measure to 40-50 milligrams everyday, to compare with severity, the condition of illness can take to 70-80 milligrams.According to report the Japanese usually absorb soybean relevant food, its soybean isoflavone equally takes to measure for the 18 mgs/person/day, still measuring with reference to differ bigger, must add again still about the 20 mgs for proper.
When should the soybean isoflavone vegetable add?
Generally speaking, the hormone complement cure best can complement before sleeping in evening, if just be considered as the soybean isoflavone vegetable to maintain generally, only persistent, have no special provision when take better.
While choosing the soybean isoflavone product, it is essential to recognize the raw material source and content, wanting to confirm the soybean source, manufacturing process method of that product first, in the meantime good soybean different Huang
The soybean isoflavone and skin hairdressing
1 Soybean differenceThe anti- oxygenation and skin of the Tong aging protection
Is the skin decrepitude the keeping of the muscle body decrepitude view view body, return all of the not yet finisheds to clear up skin currently?The decrepitude turns the mechanism for getting, but the free radicals is in the decrepitude turn get of the important function is already everyone generally accepted.Unsaturated fatty acid in the free radicals and cell membrane sour function, the creation fat lead to oxidize, its outcome C two Quans can with contain big numerator of the living creature of the ammonia Ji to hand over Lian formation?In the Schiff of the clearance?, Does the Bing sink?In?Afterbirth?Become a brown spot of fat.??Year?Of increase?, Does the anti- of Ji Ben oxidize a department?The function descend, clearance free radicals ability?Back, ?With the result that free radicals of a great deal of?Tired, is a skin?One of the important Ji systems of the nature decrepitude.The above-mentioned age increases a natural factor, besides which, some environment factors,such as sunlight, are purple outside radiation, smoke cigarette and get in touch with the computer display radiation and can also cause over a long period of time free radicals born increase in great quantities, acceleration skin decrepitude.
Does the anti- that resists the free radicals harm oxidize a department?Does the anti- that includes small numerator oxidize(As vitamin C, vitamin E, the β -carrot vegetable...etc.)oxidize with greatly molecular anti-(As lead oxide, The super oxide Qi turns , The valley Guang sweet Restore Wait for).By hurt in the free radicals and the skin decrepitude contain close relation, having already in great quantities had to oxidize the anti- oxidizing agent or anti- in recent years Is used for the research that the skin decrepitude protects the skin article.The clinical application expresses these to protect the skin article to defer the skin decrepitude contain certain result.But does the anti- oxidizeOr the anti- oxidize The outstanding weakness that is used for protecting the skin article is the property is unsteady or deeply the skin absorb result to differ, is oxidize, lost easily to live, reduce living creature thus activity.Soybean
2 Soybean difference?The Tong represses sour egg white of the Lao ammonia to arouse The activity and skin decrepitude protection
Is the skin attached by the epidermis, leather and the skin?Is the organ three parts?Become, among them leather the change of the structure is a skin decrepitude of main reason.The leather thickness of the decrepitude becomes thin, the density reduces, also mainly is because the leather gum the original content reduce to cause.Free radicals in addition to directly to the cell living creature the big numerator cause damage can also activate the skin gum keratin formation cell outside with become the growth factor and the cell factor of the fiber cell surface be subjected to the body signal to lead thoroughfare, causing to spread to record the factor AP-1 to activate unusually.Can AP-1's activating on the other hand make the skin gum synthesize an ability to reduce, activate a Ji quality gold on the other hand at first?Egg white (MMP)Express, does the MMP activity increase?, Resolve the leather gum at first.Because the leather belongs to gum to synthesize decrease at first, resolving in the meantime and then in the increment, so the gum reduces continuously at first, causing thus the skin is flabby, appearing deeper crease.A great deal of research data expresses that the Lao ammonia the sour egg white arouse Activating is unusually the key that the free radicals lies AP-1 to activate signal to conduct thoroughfare.The vitamin Ａ used by the anti- skin decrepitude is sour to protect the skin article currently is pass to repress the AP-1 activity, reduce the MMP expression to secrete, promote the leather become a fiber?The afterbirth synthesizes to secrete gum original, reduce original decomposition of gum, reduce the skin crease and improve a rough skin thus, increase leather thickness.But the vitamin AN is sour to protect the most familiar side effect in the skin article is have to the skin certain stimulative, is a skin particularly allergic the usage produces a serious allergy easily.Soybean difference?One dyestuff wood of the main composition of the Tong?Tong(also call three?Yi?Tong)is the Lao ammonia the sour egg white arouse Of particularity
3 Soybean difference?The estrogen of the Tong?The function and skin decrepitude protection
The skin is one of the organization that the estrogen produces result, does the estrogen pass with the skin?Is the estrogen of the afterbirth subjected to a body to combine the occurrence living creature?The effect has the function that the gum of promote is sour to synthesize with transparent quality at first, making skin delicate and pure white, full of the flexibility and sheen.Female after 30 years old, the estrogen secrete the function of the organ ovary to start declining, the skin would appear crease, the flexibility descend to wait for the decrepitude performance, especially?BE enter menopause behind the skin decrepitude quickly, the crease spreads to open quickly, the skin also lose flexibility very fast, no longer smooth, have something to do with menopause back the estrogen level inside the body reducing in the very great degree.Some researches express that use estrogen to act for therapy and compare those to the women after stopping menstruating?Accept the estrogen treatment of the women produce of the crease want to be few, and the skin contain the better veins and flexibility.Does the skin part use estrogen together?After stopping menstruating to the improvement the women's skin decrepitude has a function.There is research?The way uses 0.01% Cis two Chuns or 0.3% Cis three Chuns to 59 stop menstruating behind the women's partial estrogen cure, find hereafter the skin became flexibility obviously for 6 months and tightly solid, in the Ci two the Chuns and Cis the three Chuns the treatment the set, the crease depth and the pore size get an improvement obviously, callous of the humidity and gum synthesize to also increase obviously at first.However, the estrogen is the cosmetics composition usage is strictly limited, also mainly is because may the estrogen cause the mammary glands cancer and son??The risk of the film cancer increment, the skin is partial to use estrogen of dangerous possibility return small in take orally path.
Soybean difference?The numerator structure and original sex Ci inside the human body of the Tong
4 Soybean different Tong to the skin fat metabolizes of regulate the function and skin hairdressing
"Float meat" ﹙ Cellulite ﹚ is a female and familiar partial fat phenomenon, also calling "orange skin organization", "beehive organization or" sponge organization", have another because the skin descend the fat cell to become big or become more behind heap the knot hoof organization(gum original the fiber egg white) that push to the leather layer, make the cell cleft diminish, squeeze hair?Blood vessel, cause humidity and metabolize an outcome to be detained in the fat layer, together?Knotting the hoof organization would wrap up fat to become small structure, and appearance?Appear the appearance skin surface of the cave and convex gravamen, hence orange skin appeared to be like to dry by air similar and wrinkly Suo of, the appearance of the cave and convex gravamen.Soybean difference?Tong to skin?Fat generation?Regulated a function, there is obvious result towards reducing "float meat", its function mechanism mainly included two aspects as follows:?The skin has already increased thick with increase a solid function, make can betterly the holdout skin descend the fat cell aggrandizement or increase the inflation formation"float meat";?Soybean difference?Can the Tong reduce an ex- body of fat?The afterbirth develops, can also pass to repress phosphoric acid two ester sActivity, increase cell?Wreath phosphoric acid gland (CAMP)Of content, then stimulate fat decomposition Of activity, make the fat decomposition increase, the skin descends the fat organization to reduce.Switzerland section?Does the house use the soybean difference to 20 females who have the different degree thigh"float meat"?After Tong handle 6s, thigh does the thick path equally reduce a 3.8 cms, express a soybean difference?The Tong has already cleaned a function to"float meat".
On the Zong say, soybean difference?Tong can the anti- oxidize, repress sour egg white of the Lao ammonia to arouse Activity and the estrogen function etc. have another the function that the path develops the anti- skin decrepitude, can also regulate skin fat